Other Cosmetic Surgery

Plastic Surgery Fillers - Zyderm

Zyderm collagen implant is composed of highly purified bovine dermal collagen. ZYDERM collagen implant is available in two forms: ZYDERM 1 collagen implant and ZYDERM 2 collagen implant. ZYDERM 2 collagen implant contains almost twice the collagen concentration of ZYDERM 1 collagen implant. ZYDERM collagen implant is introduced into the dermis for correction of contour deficiencies of this soft tissue. After injection, the implant undergoes syneresis and, as the saline is lost, the suspended collagen condenses into a soft cohesive network of fibers. This network is responsible for restoring skin contour. Over a period of months the implant is colonized by host connective tissue cells; once established, the implant takes on the texture and appearance of normal host tissue and is subject to the same stresses and aging processes. ZYDERM 1 and ZYDERM 2 collagen implant have been employed successfully in many areas of the body to correct distensible acne scars; atrophy from disease or trauma; glabellar frown lines; nasolabial folds; rhinoplasty, skin graft or other surgically-induced irregularities; and other soft tissue defects. Severely indurated, sharply marginated and very superficial lesions (e.g., ice-pick acne scars, viral pockmarks, and superficial rhytides such as some perioral lines) have proven difficult to distend and, therefore, are difficult to correct. If a defect cannot be distended because of extensive scarring or nonelastic tissue, the course of correction will be prolonged, if correction is achievable. Deposits of even small amounts of ZYDERM collagen implant within a scar, however, often soften the tissue and allow for subsequent distension and correction.